Mostrar el registro sencillo del ítem

dc.contributor.authorMendoza, Mayra N.
dc.contributor.authorRaudsepp, Terje
dc.contributor.authorMore, Manuel J.
dc.contributor.authorGutiérrez, Gustavo A.
dc.contributor.authorPonce de León, F. Abel
dc.date.accessioned2021-11-05T19:33:44Z
dc.date.available2021-11-05T19:33:44Z
dc.date.issued2020
dc.identifier.citationMendoza, Mayra N., Terje Raudsepp, Manuel J. More, Gustavo A. Gutiérrez, and F. A. Ponce de León 2020. "Cytogenetic Mapping of 35 New Markers in the Alpaca (Vicugna pacos)" Genes 11, no. 5: 522. https://doi.org/10.3390/genes11050522es_PE
dc.identifier.urihttps://hdl.handle.net/20.500.12996/5012
dc.descriptionUniversidad Nacional Agraria La Molina. Escuela de Posgrado. Maestría en Producción Animales_PE
dc.description.abstractAlpaca is a camelid species of broad economic, biological and biomedical interest, and an essential part of the cultural and historical heritage of Peru. Recently, efforts have been made to improve knowledge of the alpaca genome, and its genetics and cytogenetics, to develop molecular tools for selection and breeding. Here, we report cytogenetic mapping of 35 new markers to 19 alpaca autosomes and the X chromosome. Twenty-eight markers represent alpaca SNPs, of which 17 are located inside or near protein-coding genes, two are in ncRNA genes and nine are intergenic. The remaining seven markers correspond to candidate genes for fiber characteristics (BMP4, COL1A2, GLI1, SFRP4), coat color (TYR) and development (CHD7, PAX7). The results take the tally of cytogenetically mapped markers in alpaca to 281, covering all 36 autosomes and the sex chromosomes. The new map assignments overall agree with human–camelid conserved synteny data, except for mapping BMP4 to VPA3, suggesting a hitherto unknown homology with HSA14. The findings validate, refine and correct the current alpaca assembly VicPac3.1 by anchoring unassigned sequence scaffolds, and ordering and orienting assigned scaffolds. The study contributes to the improvement in the alpaca reference genome and advances camelid molecular cytogenetics. View Full-Texten_US
dc.formatapplication/pdfen_US
dc.language.isoengen_US
dc.publisherMDPIes_PE
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.sourcehttps://www.mdpi.com/2073-4425/11/5/522es_PE
dc.subjectAlpacaes_PE
dc.subjectCódigo genéticoes_PE
dc.subjectMapas genéticoses_PE
dc.subjectMarcadores genéticoses_PE
dc.subjectBiotecnología animales_PE
dc.subjectTécnicas analíticases_PE
dc.subjectEvaluaciónes_PE
dc.subjectEvaluaciónes_PE
dc.subjectPerúes_PE
dc.titleCytogenetic Mapping of 35 New Markers in the Alpaca (Vicugna pacos)en_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.identifier.doihttps://doi.org/10.3390/genes11050522
dc.subject.ocdehttps://purl.org/pe-repo/ocde/ford#4.02.01es_PE
dc.publisher.countryCHes_PE
dc.type.versioninfo:eu-repo/semantics/publishedVersionen_US


Ficheros en el ítem

Thumbnail
Thumbnail

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem